Effects of mulberry leaf silage on antioxidant and immunomodulatory activity and rumen bacterial community of lambs

Titre

Effects of mulberry leaf silage on antioxidant and immunomodulatory activity and rumen bacterial community of lambs

BMC Microbiology

Créateur

Bing Wang

Hailing Luo

Sujet

Antioxidant activity

Bioactivity

Microbiome

Morus alba

Rumen

Date

12/2021

doi

10.1186/s12866-021-02311-1

uri

https://bmcmicrobiol.biomedcentral.com/articles/10.1186/s12866-021-02311-1

Résumé

Abstract

Background
Rumen is a natural fermentation system and the microorganisms inside can effectively utilize plant bioresource and interact with host metabolism. Here, analysis of rumen microbiome, together with animal performance and serum metabolism in a lamb model were performed to identify the potential use of mulberry leaf silage (MS) to replace alfalfa silage (AS) as a new functional feed resource and to mining the novel specific mulberry leaf associated rumen bacteria interact with host metabolism.


Results

The lambs fed with MS diet showed improved antioxidant capacity and immune function compared to those fed AS diet. The MS diet significantly altered rumen microbiota α- and β-diversity and taxonomic composition. Microbial analysis revealed that
Bifidobacterium, Lactobacillus
and
Schwartzia
were enhanced, and
Ruminococcaceae UCG-010
and
Lachnospiraceae_XPB1014_group
were down-regulated in the rumen of MS group. A strong association was also found between these rumen microbial taxa and host antioxidant and immunomodulatory capacity.



Conclusion
These findings indicated that mulberry leaf silage can be a high-quality feed source or bioactive pharmaceutical that is responsible for ruminant’s health benefits. The modified rumen microbial community by mulberry leaf silage were associated with the enhanced antioxidant capacity and immunomodulatory of lambs.

volume

21

numéro

1

pages

250

Titre abrégé

BMC Microbiol

Langue

en

issn

1471-2180